CYBERUP & TECH STL JOIN DISTRICT
The Downtown North Innovation District adds 2 innovation-focused institutions to its ranks: CyberUp and TechSTL.
CyberUp and TechSTL have announced their relocations to The Post Building in St. Louis' Downtown North District, adding to the innovation economy and reinforcing the City’s expanding leadership in technology, cybersecurity, data, and intelligence-driven industries.
An interior view of the high-tech renovation of the former Post-Dispatch HQ into the 300,000 SF Post Building.
Located in Downtown North, The Post Building has emerged as a center for innovation and collaboration, already home to companies including Square, Block, and Scale AI, along with federal and civic partners. Its growing tenant mix reflects renewed confidence in St. Louis as a place where companies can grow, talent can thrive, and ideas can scale.
The 18-square block Downtown North Insight District is several blocks from the recently-opened 3,100-employee, 97-acre, $1.75-billion new St. Louis HQ of the National Geospatial Intelligence Agency (NGA).
Downtown North is developing into St. Louis' newest Innovation District --- in addition to the 300,000 SF Post Building,, other key anchors in the District include the 725,000 SF Globe Building (and accompanying 75,000 SF Multi-Tenant SCIF; the T-Rex Incubator; and NGA's Moon Shot Labs.
"The decision by CyberUp and TechSTL to locate in Downtown North reflects exactly the kind of momentum 'Downtown Forward' is working to accelerate," noted Matt O'Leary, Executive Director of Downtown Forward STL. He concluded, "This is what progress looks like --- mission-driven organizations choosing to invest in the urban core."CyberUp is nationally-recognized for building a more inclusive cybersecurity workforce through youth education, technical training, and registered apprenticeships. The organization has reached more than 2,500 K-12 students, trained over 600 adults through its LevelUp programs, and maintains a 95% apprenticeship completion rate—helping position St. Louis as a leader in cybersecurity talent development.
TechSTL, the region’s Tech Council, serves the largest and most diverse professional tech network in the St. Louis area, connecting talent, startups, anchor institutions, and industry partners. A City of St. Louis–based 501(c)(6), TechSTL is establishing a long-term hub at The Post Building to deliver workforce programs, bootcamps, and industry-driven initiatives that expand access to opportunity and strengthen the region’s tech ecosystem.
TechSTL also manages the StartupSTL initiative to support the entrepreneurial ecosystem of the Metro, which is funded by the Missouri Technology Corporation.
Serving as a data steward, TechSTL recently released the 2025 StartupSTL Study, which reported startup growth increasing 50% and job creation rising 34% in just one year—evidence that locally owned businesses are driving economic momentum, particularly in professional and technical services.
With CyberUp and TechSTL establishing a presence at The Post Building, St. Louis is extending an open invitation to entrepreneurs, technologists, educators, and mission-driven organizations ready to build what’s next.
Organizations seeking to grow in a city defined by innovation, resilience, and opportunity are encouraged to join the Downtown North Innovation Community and take part in shaping the next chapter of St. Louis’ economy.
The future of St. Louis is being built here.
